Digestive & Gut
Support gut balance and easy digestion.
Gut comfort is driven mostly by fiber, hydration, and eating patterns. These options support digestion and a balanced gut, especially for occasional bloating or irregularity.
What to look for
Probiotics and enzymes that support a healthy, comfortable gut.
What the research supports
Recommended supplements
- ProbioticBeneficial bacteria that support gut balance. Meta-analyses find certain strains help symptoms of irritable bowel syndrome; effects are strain-specific, so the product matters.
- Digestive enzymesHelp break down fats, proteins, and carbohydrates, which may ease fullness or discomfort after meals for some people.
- L-glutamineAn amino acid that fuels the cells lining the gut; sometimes used to support gut-barrier health.
You'll create a free Fullscript account and check out through our professional dispensary — 20% off retail.
We may earn a commission on Fullscript purchases, at no extra cost to you. Affiliate Disclosure
Things to keep in mind
New, persistent, or severe digestive symptoms — or any blood in the stool — should be evaluated by a provider rather than self-treated. Soluble fiber and peppermint oil also have solid evidence for IBS and may be worth discussing.
Educational information only. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement.
References
Recommendations on this page are informed by published research. This is educational information, not medical advice.
- Chen M, Yuan L, Xie CR, et al. Probiotics for the management of irritable bowel syndrome: a systematic review and three-level meta-analysis. Int J Surg. 2023;109(11):3631-3647. View study →
- Khanna R, MacDonald JK, Levesque BG. Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis. J Clin Gastroenterol. 2014;48(6):505-512. View study →
- Black CJ, Yuan Y, Selinger CP, et al. Efficacy of soluble fibre, antispasmodic drugs, and gut-brain neuromodulators in irritable bowel syndrome: a systematic review and network meta-analysis. Lancet Gastroenterol Hepatol. 2020;5(2):117-131. View study →