Blood Sugar
Support healthy glucose metabolism.
Healthy glucose is driven by diet, activity, sleep, and weight. These compounds can support glucose metabolism as a complement — not a replacement for medical care.
What to look for
Compounds that support healthy glucose metabolism.
What the research supports
Recommended supplements
- BerberineA plant compound with the strongest evidence in this group; meta-analyses show it lowers blood glucose in type 2 diabetes.
- ChromiumA trace mineral involved in insulin action. Evidence is mixed, with the most consistent benefit a modest glucose improvement in people who already have diabetes.
- Alpha-lipoic acidAn antioxidant that a meta-analysis found improved glucose control in metabolic conditions.
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Things to keep in mind
These can lower blood sugar and may interact with diabetes medications — never adjust medication on your own, and coordinate closely with your provider. Berberine interacts with many drugs.
Educational information only. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement.
References
Recommendations on this page are informed by published research. This is educational information, not medical advice.
- Xie W, Su F, Wang G, et al. Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis. Front Pharmacol. 2022;13:1015045. View study →
- Suksomboon N, Poolsup N, Yuwanakorn A. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes. J Clin Pharm Ther. 2014;39(3):292-306. View study →Note: Results are mixed; the most consistent benefit is a modest improvement in blood sugar among people who already have diabetes.
- Akbari M, Ostadmohammadi V, Lankarani KB, et al. The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. Metabolism. 2018;87:56-69. View study →