Melatonin
Your body's own sleep-timing hormone, used as a short-term sleep aid.
Want to try Melatonin?
See our pick — chosen for form and dose — in our professional dispensary. Please read Safety & interactions first.
Buy on Fullscript →You'll create a free Fullscript account and check out through our professional dispensary — 20% off retail.
We may earn a commission on Fullscript purchases, at no extra cost to you. Affiliate Disclosure
What it is
Melatonin is a hormone your brain releases as it gets dark to signal that it's time to sleep. As a supplement, it's used less as a sedative and more as a way to nudge your body clock.
How it works
Melatonin is the hormone your pineal gland releases as darkness falls, signaling to your body clock that it's time to sleep. As a supplement it acts less like a sedative and more like a timing cue — nudging your internal clock earlier or later, which is why it shines for jet lag and shifted schedules rather than acting as a knockout pill.
What it's been studied for
Used to fall asleep faster and to reset the body clock for jet lag or shift work.
What the evidence shows
Meta-analyses show melatonin modestly shortens the time it takes to fall asleep, with its clearest value for jet lag and shifted schedules. Dose-response analysis suggests lower doses often work as well as higher ones.
Who should consider it
It's most useful for jet lag, shift workers, people whose body clock runs late (they can't fall asleep until very late), and occasional trouble falling asleep. It's less suited to people who wake in the middle of the night from other causes. Talk with a provider about use in children or during pregnancy.
Amounts commonly studied
Studies commonly use 0.5-5 mg taken 30-60 minutes before bed. More is not better — start low.
How to take it
Take a low dose — 0.5-3 mg — about 30 to 60 minutes before your target bedtime; more is not better, and high doses mainly add grogginess. For jet lag, take it at bedtime in the new time zone. Dim the lights and avoid screens afterward, since bright light blunts its effect. Use it short-term rather than every night indefinitely.
Forms & absorption
Immediate-release helps with falling asleep; extended-release is marketed for staying asleep. Quality and actual content vary widely between brands, so third-party testing matters here.
Food sources
Only trace amounts occur in foods like tart cherries, grapes, and some nuts — not enough to match a supplement dose. Your body makes its own in response to darkness, which good light habits support.
Safety & interactions
Considered safe for short-term use; can cause grogginess, vivid dreams, or headache. Best used short-term rather than nightly indefinitely. Discuss use in children or during pregnancy with a provider.
Myths & what it won't do
Myth: a higher dose means deeper sleep. Reality: low doses often work as well as high ones, and large amounts mostly add next-day grogginess and vivid dreams. Myth: melatonin is a sleeping pill. Reality: it's a body-clock signal — great for timing problems like jet lag, but not a strong sedative for every kind of insomnia. Myth: the label equals what's in the bottle. Reality: independent testing has found melatonin content varies widely, so a tested brand matters.
Common questions
- Is it safe to take every night?
- It's considered safe short-term. For ongoing sleep problems it's better to find the cause than to rely on it nightly indefinitely — talk with your provider.
- Will I become dependent on it?
- Melatonin isn't considered habit-forming the way some sleep drugs are, but relying on any sleep aid can become a habit; use it as a tool, not a crutch.
- Why do I feel groggy the next day?
- Usually the dose is too high or taken too late. Try a smaller dose (0.5-1 mg) taken a bit earlier in the evening.
The amounts listed here are what published research has used — not a prescription or a recommended dose for you. Confirm anything you plan to take with your own healthcare provider, especially if you take medications, are pregnant or nursing, or have a health condition.
Related goals
Research on Melatonin
Recommendations on this page are informed by published research. This is educational information, not medical advice.
- Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8(5):e63773. View study →
- Cruz-Sanabria F, Bruno S, Crippa A, et al. Optimizing the Time and Dose of Melatonin as a Sleep-Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose-Response Meta-Analysis. J Pineal Res. 2024;76(5):e12985. View study →